Objective:
The course aims to give a solid basis in basic bioinformatics methods. It covers the theories, algorithms and practical applications of computer-based methodology for the analysis of Nucleic and protein sequences.

On completion of the course, the student should be able to:
- account for the fundamental concepts within bioinformatics
- independently carry out homology analyses of both protein - and DNA sequences and interpret the results
- use the most common commands in Unix/Linux,
- independently build a "workbench" for bioinformatics with publicly available software suited to the students own needs,
- use biological databases
- independently use technologies and analysis of Next Generation Sequencing data. and
- manage methods for the analysis of expression data.

Content:
The course covers bioinformatics methods such as theories, algorithms and practical applications in computer-based methodology for the analysis of DNA and protein sequences. The course also covers theories for the analysis of RNAseq expression data and different analytical methods related to Next Generation Sequencing.

Topics to be covered includes: biological databases, homology analyses, gene analyses (emphasis on software packages like e.g. EMBOSS and UGENE), web-based analytical tools, Unix OS, comparative genomics, functional genomics, GWAS analysis, molecular evolution, RNAseq expression analysis, annotation of new genomes.

The course is based on lectures, exercises and project work. Apart from the written and the oral examination, compulsory components occur within e. g. exercises, project work and laboratory sessions.