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and Keywords: Single cell

and Scientific topics: Drug discovery

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Workshops and courses

A guide to identifying and prioritising drug targets with the Open Targets Platform

19 May 2021

Online
Drug discovery Fermentation Microbial ecosystems webinar Ensembl Genomes DNA & RNA (dna-rna) UniProt: The Universal Protein Resource Proteins (proteins) BLAST Open Targets Platform Cross domain (cross-domain) Chemical biology (chemical-biology) Drug target identification UniRule ARBA Automated annotation MetaboLights: Metabolomics repository and reference database Chemical Entities of Biological Interest ChEBI Metabolites Molecular building blocks of life Human Cell Atlas Data Coordination Platform Single-cell transcriptomics HCA data portal Programmatic access API Python Complex Portal macromolecular assembly InterPro Boolean modelling Europe PubMed Central Literature (literature) Open access Protein Data Bank in Europe - Knowledge Base 3D structure AlphaFold Database DeepMind Artificial intelligence AI Structure prediction cancer Boolean European Nucleotide Archive Data archive Raw sequencing data RNAcentral Non-coding RNA ncRNA GPU Data protection Job dispatcher Bioimage analysis resource Accessibility Missense variation Biostatistics Rfam non-coding RNA Infernal software Sequence annotation Root microbiome Abiotic stress land management Plant genotype Plant webinar series HPC database development cross-linked databases Plant database data infrastructure Plant breeding Data standards data managemnet data sharing Hyb-Seq method Flowering plants Crop improvement Pangenomics Pangenomes Virtual humans Drug-target identification plant-microbe interactions Spatial transcriptomics Plant research Drug targets Machine learning Mathematical modelling plant science Data integration plant-environment interaction Phenotyping field phenotyping Deep phenotyping EOSC-Life NHGRI-EBI GWAS Catalog clinical data genome-wide association Proteomics Proteomes Peptide search plants European Variation Archive EVA Variant clusters Variant data annotation Constraint-based metabolic modelling UniProt knowledgebase protein variant impact disease-associated protein variants Bioethics FAIR principles ELSI cohort data translational research BioModels database Mathematical modeling Reproducibity Systems biology models workflows federated analysis polygenic risk scores IntAct Molecular Interaction Database PSICQUIC IMEx Complex portal Agent-based modelling Macrophages Tumorigenesis Ensembl Training (Training) On-demand teaching introduction Building blocks Data analysis COSMIC Cancer mutation Somatic mutation ChEMBL: Bioactive data for drug discovery Chemical compounds drug-like molecules Chemogenomics Biocurator Programming Data management Green Algorithms Open data Environmental impact Carbon footprint HPC workflows Orchestrator Gene expression (gene-expression) Chemosensitivity assay Experimental protocols Drug screening MICHA European Genome-phenome Archive EGA restricted access UniProt Introduction UniProtKB Proteome Protein Data Bank in Europe genes Introductory GDPR Data security Expression Atlas Pfam protein sequence search Domain architecture Protein taxonomy AI structure prediction COVID-19 Coronavirus COVID-19 Data Portal Virology Computational simulations Signalling prior knowledge Cancer therapy response PRIDE: The Proteomics Identifications Database protein structure prediction AI system Competency framework Publication Journal club Preprints Aggregated view Structural similarity PPI networks Cell signaling Malaria Biological networks Graph theory Building biological networks Biocuration Information Manager Industry Rare-variant Variant association SKAT Sensitive data Human cohort data FAIR Gene Ontology International Mouse Phenotyping Consortium Portal Biocurators biocuration programming skills training career development Cell-level simulations Personalised medicine PerMedCoE Single cell Phenotype Genome-Wide Association Studies Genome Signaling networks BioImage Archive REST Funding UniChem: Chemical Structure Cross-referencing Bioactivity data Drug-like compounds BioStudies Database EBI Search Finding data World Sight Day Eye development Eye disease Open software Metadata Web Services Dbfetch Database fetch programmatic access Open Targets Protein structure prediction Colab notebooks RESTful API RESTful Web Services PDBe Ligand binding sites Protein families Protein functional analysis Protein sequences Data curation Biomolecular sequences Cytoscape PsyArXiv Psychology

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A guide to identifying and prioritising drug targets with the Open Targets Platform