Date: 1 - 11 February 2021

This series of workshops will explore EMBL-EBI data resources for genomics, transcriptomics, protein sequences, structures and interactions, and chemical biology. Each half-day workshop will introduce participants to browsing, searching, retrieving, and conducting a basic analysis of a wide range of biological data types. 

Two workshops will cover the Ensembl genome browser, where researchers can explore annotated genomes and features of interest including genes, transcripts, and variants. Participants will also be introduced to the Variant Effect Predictor (VEP) tool and BioMart for bulk data download.

Functional genomics resources - Array Express, Expression Atlas - will introduce public data derived from transcriptomics experiments and provide instruction on how to begin investigating biological functions. Participants will also cover the Single-cell Expression Atlas and the expression data from individual cell sequencing.

Three workshops will explore resources dedicated to protein data, covering UniProt, the PDBe, IntAct, the Complex Portal, and Reactome. These topics will provide overviews of protein sequence, structure, and interactions; allowing participants to gain a greater understanding of the role played by proteins in the cell.

The final workshop will cover the EBI's chemical biology resources ChEBI and MetaboLights. Participants will learn how to access information on chemical entities of biological interest, and the myriad metabolites found in metabolomics experiements.

Virtual workshop

Participants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through trainer-led demonstrations and personal exercises on each resource. Live sessions will be delivered using Zoom with additional support and communication from the host, trainer and, resource specialists in the chat stream.

Keywords: Protein Data Bank in Europe , Ensembl , Proteins (proteins), Structures (structures), UniProt: The Universal Protein Resource , Expression Atlas , IntAct Molecular Interaction Database , Complex Portal , Reactome pathways database , DNA & RNA (dna-rna), Gene expression (gene-expression), Systems (systems), Chemical biology (chemical-biology), ArrayExpress Archive of Functional Genomics Data , Chemical Entities of Biological Interest , MetaboLights: Metabolomics repository and reference database

Target audience: This workshop is aimed at PhD students within the PhD programme "Genetics, Molecular and Cellular Biology" (University of Pavia) and the PhD programmme "Biomolecular Sciences and Biotechnology" (IUSS, University School for Advanced Studies Pavia. No knowledge of programming is required, but an undergraduate level knowledge of biology or molecular biology would be useful.

Capacity: 30


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