e-learning

Comparative gene analysis in unannotated genomes

Abstract

Despite the rapidly increasing number of fully assembled genomes few genomes are well annotated. This is especially true for large eukaryotic genomes with their complex gene structure and abundance of pseudogenes. And of course do not forget about the Murthy's law: if you are interested in a particular gene the chances are that it will not be annotated in your genome of interest. In this tutorial we will demonstrate how to compare gene structures across a set of vertebrate genomes. So ...

About This Material

This is a Hands-on Tutorial from the GTN which is usable either for individual self-study, or as a teaching material in a classroom.

Questions this will address

  • I have several genomes assemblies that are not annotated (or I do not trust annotations)
  • I am interested to compare structure of a particular gene across these genome assemblies
  • How do I do that?

Learning Objectives

  • Provide a quick method for identifying genes of interest in unannotated or newly assembled genomes

Licence: Creative Commons Attribution 4.0 International

Keywords: Genome Annotation, annotation, cookbook, eukaryote, evolution, microgalaxy, prokaryote, vgp

Target audience: Students

Resource type: e-learning

Version: 8

Status: Active

Prerequisites:

  • Galaxy Basics for genomics
  • Introduction to Galaxy Analyses
  • Using dataset collections

Learning objectives:

  • Provide a quick method for identifying genes of interest in unannotated or newly assembled genomes

Date modified: 2024-03-18

Date published: 2022-09-08

Authors: Anton Nekrutenko

Scientific topics: Genomics, Gene and protein families, Sequence analysis, Phylogeny


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