DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Questions of the tutorial:

• What is methylation and why it cannot be recognised by a normal NGS procedure?
• Can a different methylation influence the expression of a gene? How?
• Which tools you can use to analyse methylation data?

Objectives of the tutorial:

• Learn how to analyse methylation data
• Get a first intuition what are common pitfalls.