Tutorial
Epigenetics - Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.
Questions of the tutorial:
- Why is a Hi-C analysis useful?
- What is 'chromosome conformation capture'?
- What are main steps in order to generate and plot a Hi-C contact matrix?
Resource type: Tutorial
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