Exome sequencing means that all protein-coding genes in a genome are sequenced

Questions of the tutorial:

• What is mapping-by-sequencing?
• How can it help you identify the causative mutation in phenotypic mutants isolated from genetic screens?

Objectives of the tutorial:

• Use joint variant calling and extraction to facilitate variant comparison across samples
• Perform variant linkage analyses for phenotypically selected recombinant progeny
• Filter, annotate and report lists of variants