Exome sequencing means that all protein-coding genes in a genome are sequenced

Questions of the tutorial:

• How do we detect differences between a set of reads from a microorganism and a reference genome

Objectives of the tutorial:

• Find variants between a reference genome and a set of reads
• Visualise the SNP in context of the reads aligned to the genome
• Determine the effect of those variants on genomic features
• Understand if the SNP is potentially affecting the phenotype